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Articles by Michael P. Balogh

Michael P. Balogh

"MS - The Practical Art" Editor

Michael P. Balogh is the editor of "MS - The Practical Art," and is widely recognized as one of the leading experts in the field of mass spectrometry. He is currently Principal Scientist, LC-MS Technology Development, with Waters Corp., Milford, Massachusetts, and is a member of LCGC's editorial advisory board.

Articles
Commercialization of LC–MS: The Second Decade
August 1, 2009

Columnist Michael Balogh looks back on a 1997 LCGC article he wrote, and examines how many technological advances the field of MS has witnessed in the decade since.

Alternative Futures: Biofuels and Mass Spectrometry
April 1, 2009

The use of mass spectrometry to study biofuels is examined and the advantages and disadvantages are explored.

A Mass Spectrometry Primer, Part IV
February 1, 2009

This column completes the multipart MS primer with a list of terms derived from common usage throughout various industries.

A Mass Spectrometry Primer, Part III
December 1, 2008

Part III concludes the print version of our three-part series, "A Mass Spectrometry Primer," with the glossary to follow in a fourth and final installment.

The Changing Face of LC–MS: From Experts to Users
November 1, 2008

Two decades ago, MS was the preserve of experts and skilled technicians as the instrumentation required constant attention and adjustment. At that time, liquid chromatography (LC)–MS was in its infancy and atmospheric pressure ionization (API) source interfacing was just beginning. Samples requiring analysis were passed from the requesting scientist to these "experts for analysis." The samples would be analyzed, processed, and interpreted, and the results returned via a written report. Two decades later, the users and capabilities of LC–MS have changed significantly. Now mass spectrometers and LC–MS systems are ubiquitous in the analytical laboratory, especially in the pharmaceutical industry. These instruments are used by a wide variety of scientists for a diverse range of tasks, from purity screening in medicinal chemistry, to the quantification of drugs in blood and the identification of proteins for biomarker discovery. The usability of the current MS platforms has improved..

A Mass Spectrometry Primer, Part II
October 1, 2008

Part II of this three-part series focuses on comparing operation and performance of the most well known mass spectrometers.

A Mass Spectrometry Primer: Part I
August 1, 2008

Michael Balogh begins a three-part overview series, answering questions about mass spectrometers, their use and capabilities, and including links to more detailed further reading in readily available articles written for the nonspecialist.

Determining Health Hazards: A Look into the EPA Practice
June 1, 2008

The matter of perfluorinated compounds (PFCs) came to focus at the United States Environmental Protection Agency (EPA) some eight years ago.

Petroleomics — MS from the Ocean Floor
March 1, 2008

Recent work suggests that the practical value of hyphenated techniques is limited by difficulties inherent in achieving definitive compositional answers in general MS. This article argues that it is not impossible in certain cases.

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