Column: LC Troubleshooting

LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, columnist John Dolan is able to highlight common problems and provide remedies for them.

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LC Troubleshooting Strategies

December 1, 2009
By:John W. Dolan

John Dolan looks at ways to get to the root of some of the most common problems encountered in the lab.

Too Little or Too Much

January 1, 2010
By:John W. Dolan

What should you do when a peak is too small or too large?

Too Little or Too Much

January 1, 2010
By:John W. Dolan

What to do when a peak is too small or too large

Kinetic Plots Made Easy

December 1, 2009
By:Uwe D. Neue

Guest "LC Troubleshooting" columnist Uwe Neue unravels the mysteries surrounding kinetic plots to make them accessible to everyone

Kinetic Plots Made Easy

November 1, 2009
By:Uwe D. Neue

Guest author Uwe Neue develops the principle of kinetic plots from scratch to make them more accessible to a wider audience.

Integration Problems

October 1, 2009
By:John W. Dolan

What's the best way to integrate a peak?

Too Many Changes

October 1, 2009
By:John W. Dolan

Remember the rule of one — change just one thing at a time.

Calibration Curves, Part 5: Curve Weighting

September 1, 2009
By:John W. Dolan

When is curve weighting a good idea?

Method or System?

September 1, 2009
By:John W. Dolan

This month's column discusses the type of problems one can encounter when using methods supplied to us by other.

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