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Peer-reviewed research on HPLC - high performance liquid chromatography. Analytical chemistry info for separation scientists & chromatographers - from LCGC.

Trends in HPLC Column Usage

November 1, 2009

In this installment of "Column Watch," Ron Majors looks at the results of a recent HPLC column survey conducted by LCGC North America.

Buffer Considerations for LC and LC–MS

November 1, 2009

The authors examine some critical factors with regard to buffers in LC and LC-MS research.

Analytical Method Validation: Back to Basics, Part I

November 1, 2009

The authors present the first installment in their examination of the basics of method validation.

Kinetic Plots Made Easy

November 1, 2009

Guest author Uwe Neue develops the principle of kinetic plots from scratch to make them more accessible to a wider audience.

Analysing Red Clover by HPLC

September 1, 2010

A simple rapid HPLC method for simultaneously determiing formononetin, biochanin A, daidzen and genistein in Red Clover

Plasma Analysis

August 6, 2010

The analysis of clozapine and norclozapine in plasma using automated on-line sample preparation and LC–MS/MS

System Contamination

August 1, 2010

Deterioration of the separation can result from many causes. This month's column looks at some techniques to isolate the problem source.

Early Adventures in Chromatography: The Story of a "Recovering" Electrochemist

August 1, 2010

Well-known industry veteran and LCGC EAB member Peter Carr looks back at the early days of the chromatography field and reflects on his own experiences.

Why does it take so long to validate a CDS?

August 1, 2010

The author examines the process of validating a CDS and describes the trials along the way such as speed of validation, risk management, and so forth.

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