UPCOMING WEBCASTS


Thursday, August 12, 2010
10:00 AM PT; 1:00 PM ET
Molecular Imaging for Localization and Distribution of Proteins, Peptides, Drugs and Metabolites by Mass Spectrometry

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This presentation will detail the use of both MALDI-TOF and FTMS Mass Spectrometers to measure the tissue distribution of a variety of proteins, peptides, lipids, or small molecule drugs and metabolites in various tissues. Examples of tissue distribution for a variety of proteins in various tissues and simultaneous determination of the localization of small molecule drugs and metabolites administered at therapeutic dosage levels in time course studies will also be presented. These MS systems were tested to assess their capabilities in terms of accuracy, data quality, sensitivity, flexibility to analyze different types of molecules, automated analysis capabilities, and general utility in both small molecule and protein analyses. Results from various Mass Spectrometry technologies will be presented and compared.

Sponsored by: Bruker Daltonics Inc.

Tuesday, August 17, 2010
8:00 AM PT; 11:00 AM ET
Fundamentals of Solid Phase Extraction

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The Essential Guide from LCGC's CHROMacademy presents the definitive webcast on Understanding Mechanisms in Solid Phase Extraction. In this session Tony Taylor (CHROMacademy Technical Director), presents the fundamentals of SPE protocol design, sorbent selection, optimization strategies for each protocol stage and topis of best processing practice all supported by Interactive Multi-Media from The CHROMacademy. The session will also consider key topics such as selection of the correct sorbent chemistry and bed mass, generic polymer resins, the importance of sample and sorbent preparation, strategies for optimizing selectivity through aggressive sorbent washing optimized eluent strengths as well as some fantastic topics on improving extraction selectivity and effciency. A must see for everyone using or developing methods for using solid phase extraction.

Sponsored by: Thermo Fisher Scientific/Chromacademy

Wednesday, September 1, 2010
8:00 AM PT; 11:00 AM ET; 4:00 PM GMT
Method Development in Packed Column Supercritical Fluid Chromatography

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SFC can be 3-5 times faster than HPLC for the same result without the expense of high temperature, sub2µm particles, and extremely high pressure. Normal phase chromatography is best accomplished today by pcSFC. Experimental strategies leading to successful packed column supercritical fluid chromatography (pcSFC) will be presented.

Sponsored by: Agilent Technologies

Thursday, September 16, 2010
8:00 AM PT; 11:00 AM ET; 4:00 PM GMT
Integrated Solutions to Rapid, QbD-Compliant Method Development

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Improving productivity to bring new drugs to market more quickly while reducing costs is the focus of everyone involved in pharmaceutical development. One way to make a dramatic impact on productivity is to improve the speed and output of your chromatographic method development, an activity that is performed throughout the entire drug development process. New strategies and technologies that automate the method development workflow, reduce the analysis time, and ensure that robustness is built into the method can reduce operating costs, maximize asset utilization, and improve a drug?s quality and time to market. UltraPerformance Liquid Chromatography (UPLC) has established itself as the standard in liquid chromatographic methods and its use continues to expand into all areas of the drug development lifecycle. In addition, the FDA and ICH Quality by Design (QbD) guidances state that a best practices approach to chromatographic method development incorporates robustness into the method development process. Recent advances in instrumentation and software now allow this to be achieved in a simpler manner than previously possible. This webcast will present an easy to use, rapid, automated approach to the development of robust, QbD-applied UPLC methods using a completely integrated method development instrument and software. It will also present case studies of its successful use.

Sponsored by: Waters Corporation

Wednesday, November 10, 2010
8:00 AM PT; 11:00 AM ET; 4:00 PM GMT
LC and LC/MS in the Pharmaceutical Industry: Metabolite Analysis

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One of the cores of pharmaceutical research is metabolite analysis and the workhorse technique application area continues to be LC and LC-MS. Here, LCGC's experts examine this topic for the largest segment of its readership.

Sponsored by: Agilent Technologies